In move echoing the science fiction movie classic
Fantastic
Voyage, doctors have successfully sent a medical robot into a living
patient.
Researchers at the Department of Computer Engineering and Institute of
Biomedical Engineering at
École
Polytechnique de Montréal were able to control the wireless device inside an
artery using a clinical magnetic resonance imaging (MRI) system.
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The breakthrough marks the first time that doctors have controlled a
micro-device inside an artery.
The work was carried out under the direction of professor Sylvain Martel,
holder of the Canada Research chair in Micro/Nanosystem Development,
Construction and Validation, and in collaboration with researchers at the
Centre
hospitalier de l'Université de Montréal (Chum).
The team succeeded in injecting a prototype device within the carotid artery
of a living animal, propelling it at speed of 10 centimetres per second and
controlling it by means of software programs.
Encouraged by the results, staff at the Polytechnique NanoRobotics Laboratory
are working to further reduce the size of the devices so that, within a few
years, they could navigate inside smaller blood vessels.
"The injection and control of nano-robots inside the human body, which
contains nearly 100,000 kilometres of blood vessels, is a promising avenue that
could enable interventional medicine to target sites that are inaccessible using
modern medical instruments such as catheters," Professor Martel explained.
"In collaboration with our scientific partners, Polytechnique researchers
have begun developing several types of micro- and nano-devices for novel
applications, such as targeted delivery of medications to tumour sites and
diagnoses using navigable bio-sensors."
The results of this breakthrough were published by Professor Martel and 10
co-authors from École Polytechnique de Montréal and the Chum on March 14 in the
scientific journal Applied Physics Letters.
Patent applications have been submitted for this method of real-time
monitoring and guidance of devices for minimally invasive surgeries using MRI.
Commercialisation of the technology has been entrusted to Gestion Univalor LP.
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